课题组网站：http://poc.nankai.edu.cn

研究领域：主要研究方向包括物理有机化学在不对称催化反应机理研究中的应用、新型手性质子酸催化剂设计及应用、含有手性季碳中心化合物的不对称合成等。

1998-2002 南开大学化学学院本科 导师：程津培 院士

2002-2007 南开大学化学学院直攻博 导师：程津培 院士

2007-2009 中国科学院化学研究所博士后 合作导师：罗三中 研究员

2009-2010 中国科学院化学研究所 副研究员

2010-2017 南开大学化学学院 副教授

2018-至今 南开大学化学学院 教授

目前已在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Nat. Commun.、ACS Catal.、Chem. Sci.、iScience.、Chem. Commun.、Org. Lett.等刊物上发表论文100篇，其中第一或通讯作者论文80篇，多篇得到Synfacts专文评述，多篇文章成为当季点击下载最多的文章之一。

近期代表作：

[1] Y.-L. Pan, H. Zheng, J. Wang, C. Yang, X. Li,* J. –P. Cheng, “Enantioselective Allylation of Oxocarbenium Ions Catalyzed by Bi(OAc)3/Chiral Phosphoric Acid”, ACS Catal. 2020, 10, 8069-8076.

[2] W. Zhang, X.-X. Xiang, J. Chen, C. Yang, Y.-L. Pan, J. –P. Cheng, Q. Meng,* X. Li,* “Direct C-H Difluoromethylation of Heterocycles via Organic Photoredox Catalysis”, Nat. Commun. 2020, 11, 638-647.

[3] Q. Zhang, Y. Li, J. Wang, C. Yang, C.-J. Liu, X. Li,* J. –P. Cheng, “B(C6F5)3/Chiral Phosphoric Acid Catalyzed Ketimine-ene Reaction of 2-Aryl-3H-indol-3-ones and ?-Methylstyrenes”, Angew. Chem. Int. Ed. 2020, 59, 4550-4556.

[4] G. –H. Yang, H. Zheng, X. Li,* J. –P. Cheng, “Asymmetric Synthesis of Axially Chiral Phosphamides via Atroposelective N-allylic Alkylation”, ACS Catal. 2020, 10, 2324-2333.

[5] G. –H. Yang, Y. Li, X. Li,* J. –P. Cheng, “Access to P-Chiral Phosphine Oxides by Enantioselective Allylic Alkylation of Bisphenols”, Chem. Sci. 2019, 10, 4322-4327.

[6] J. Wang, Q. Zhang, B. Zhou, C. Yang, X. Li,* J. –P. Cheng, “Bi(III)-Catalyzed Enantioselective Allylation Reactions of Ketimines” iScence, 2019, 16, 511-523.

[7] S. Li, C. Yang, Q. Wu, X. Li,* J. –P. Cheng, “Atroposelective Catalytic Asymmetric Allylic Alkylation Reaction for Axially Chiral Anilides with Achiral Morita–Baylis–Hillman Carbonates” J. Am. Chem. Soc. 2018, 140, 12836-12843.

[8] C. Yang, E. Zhang, X. Li,* J. –P. Cheng,* “Asymmetric Conjugate Addition of Benzofuran-2-ones to Alkyl 2-Phthalimidoacrylates: Modeling Structure-Stereoselectivity Relationship Using Steric and Electronic Parameters”, Angew. Chem. Int. Ed. 2016, 55, 6506-6510.

[9] N. Dong, Z. –P. Zhang, X. S. Xue, X. Li,* J. –P. Cheng, “Phosphoric Acid Catalyzed Asymmetric 1,6-Conjugate Addition of Thioacetic Acid to para-Quinone Methides”, Angew. Chem. Int. Ed. 2016, 55, 1460-1464.