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研究领域：

Research Interest Areas:

1. Organophosphorus Chemistry;

2. Organic Synthetic Chemistry;

3. Electronic Chemicals

1985－1989年，华中师范大学化学系本科

1989－1994年，南开大学元素有机化学研究所研究生

1994－1998年，南开大学讲师、副教授

1998－2004年，南非、美国博士后

2004年至今，南开大学化学学院教授

已发表学术论文150余篇。最近的代表性论文如下：

1. Enantioselective [4+1] annulation of α,β-unsaturated imines with allylic carbonates catalyzed by a hybrid p-chiral phosphine oxide-phosphine, H. Li, J. Luo, B. Li, X. Yi, Z. He, Org. Lett. 2017, 19, 5637-5640.

2. P(NMe2)3-mediated reductive (1+4) annulation reaction of isatins with nitroalkenes: an access to spirooxindolyl isoxazoline N-oxides and their corresponding isoxazolines, Y. Liu, H. Li, X. Zhou, Z. He, J. Org. Chem. 2017, 82, 10997-11007.

3. Phosphine-catalyzed (4 + 1) annulation of o-hydroxyphenyl and o-aminophenyl ketones with allylic carbonates: syntheses and transformations of 3-hydroxy-2,3-disubstituted dihydrobenzofurans and indolines, Z. Qin, W. Liu, D. Wang, Z. He, J. Org. Chem. 2016, 81, 4690-4700.

4. Divergent reactivity of nitrocyclopropanes with Huisgen zwitterions and facile syntheses of 3-alkoxy pyrazolines and pyrazoles, C. Yang, W. Liu, Z. He, Z. He, Org. Lett. 2016, 18, 4936-4939.

5. Annulation reaction of 3-acylmethylidene oxindoles with Huisgen zwitterions and its applications in the syntheses of pyrrolo[4,3,2-de]quinolinones and marine alkaloids Ammosamides, C. Yang, X. Chen, T. Tang, Z. He, Org. Lett. 2016, 18, 1486-1489.

6. P(NMe2)3-mediated reductive intramolecular annulation of benzoylformates tethered with a trisubstituted alkene unit and synthesis of 2,2-disubstituted 2H-chromenes, J. Zhang, Y. Qiu, B. Zhang, Z. Huang, Z. He, Org. Lett. 2021, 23, 1880-1885. 

7. PIII-mediated intramolecular cyclopropanation and metal-free synthesis of cyclopropane-fused heterocycles, J. Zhang, J. Hao, Z. Huang, J. Han, Z. He, Chem. Commun. 2020, 56, 10251-10254. 

8. Enantiopure chiral phosphines bearing a sulfinyl group and their application in catalytic enantiodivergent synthesis of polysubstituted pyrrolines, H. Li, B. Li, J. Zeng, C. Jiang, Z. He, Adv. Synth. Catal. 2020, 362, 2760-2766.