1990年8月-1992年7月,四川师范学院,学士学位;
1994年9月-1997年7月,南开大学元素有机化学研究所,硕士学位;
2000年9月-2003年7月,南开大学元素有机化学研究所,博士学位;
2007年和2013年两次获得天津市自然科学一等奖(R2);
2008年获得教育部“新世纪人才计划”支持;
2012年获得“Thieme Chemistry Journals Award”;
2013年得到了国家自然科学杰出青年基金资助;
2019年获得国家自然科学奖一等奖(R2)
已发展了系列羰基化合物的高效不对称催化氢化新反应,实现了多样性手性醇的高效、高选择性不对称合成,并基于多样性手性醇的高效合成新反应和新方法建立和发展了包括加蓝他敏等复杂手性天然产物分子的不对称全合成新策略和新路线,显著提高了手性天然产物的合成效率和选择性。已发表包括J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem. Sci., Org. Lett.等在内的学术论文110余篇。代表性研究论文如下:1. Huai-Yu Bin, Ke Wang, Dan Yang, Xiao-Hui Yang, Jian-Hua Xie,* Qi-Lin Zhou. Scalable Enantioselective Total Synthesis of (‐)‐Goniomitine. Angew. Chem., Int. Ed. 2019, 58, 1174-1177.
2. Yun-Ting Liu, Lin-Ping Li, Jian-Hua Xie*, Qi-Lin Zhou, Divergent Asymmetric Total Synthesis of Mulinane Diterpenoids, Angew. Chem. Int. Ed. 2017 56, 12708-12711.
3. Xiao-Hui Yang, Hai-Tao Yue, Na Yu, Yi-Pan Li, Jian-Hua Xie*, Qi-Lin Zhou*. Iridium-Catalyzed Asymmetric Hydrogenation of Racemic α-Substituted Lactones to Chiral Diols, Chem. Sci. 2017, 8, 1811-1814.
4. Deng-Hui Bao, Hui-Ling Wu, Chao-Lun Liu, Jian-Hua Xie*, Qi-Lin Zhou*, Development of Chiral Spiro P-N-S Ligands for Iridium-Catalyzed Asymmetric Hydrogenation of β-Alkyl-β-Ketoesters, Angew. Chem. Int. Ed. 2015, 54, 8791-8794.
5. Xiao-Hui Yang, Ke Wang, Shou-Fei Zhu, Jian-Hua Xie*, Qi-Lin Zhou*. Remote Ester Group Leads to Efficient Kinetic Resolution of Racemic Aliphatic Alcohols via Asymmetric Hydrogenation, J. Am. Chem. Soc. 2014, 136, 17426–17429.
6. Xiao-Hui Yang, Jian-Hua Xie*, Wei-Peng Liu, Qi-Lin Zhou*, Catalytic Asymmetric Hydrogenation of δ-Ketoesters: Highly Efficient Approach to Chiral 1,5-Diols, Angew. Chem. Int. Ed. 2013, 52, 7833-7836.
7. Chong Liu, Jian-Hua Xie*, Ya-Li Li, Ji-Qiang Chen, Qi-Lin Zhou*, Asymmetric Hydrogenation of α,α'-Disubstituted Cycloketones via Dynamic Kinetic Resolution: An Efficient Construction of Chiral Diols with Three Contiguous Stereocenters, Angew. Chem. Int. Ed. 2013, 52, 593–596.
8. Jian-Hua Xie*, Xiao-Yan Liu, Xiao-Hui Yang, Jian-Bo Xie, Li-Xin Wang, Qi-Lin Zhou*, Chiral Iridium Catalysts Bearing Spiro Pyridine-Aminophosphine Liangds Enable Highly Efficient Asymmetric Hydrogenation of β-Aryl β-Ketoesters, Angew. Chem. Int. Ed. 2012, 51, 201-203.
9. Jian-Hua Xie*; Xiao-Yan Liu, Jian-Bo Xie, Li-Xin Wang, Qi-Lin Zhou*, An Additional Coordination Group Leads to Extremely Efficient Chiral Iridium Catalysts for Asymmetric Hydrogenation of Ketones, Angew. Chem. Int. Ed. 2011, 50, 7329-7332.
10. Jian-Bo Xie, Jian-Hua Xie*, Xiao-Yan Liu, Wei-Ling Kong, Shen Li, and Qi-Lin Zhou*, Highly enantioselective hydrogenation of α-arylmethylene cycloalkanones catalyzed by iridium complexes of chiral spiro aminophosphine ligands, J. Am. Chem. Soc. 2010, 132, 4538-4539.
已培养博士6名,硕士7名