主要研究领域:合成有机化学、有机材料、农药化学
1)杂原子链接的乙烯基炔丙基合成子在杂环合成中的应用。如乙烯基炔丙基醚(或胺)合成子用于呋喃、吡咯、吡啶和稠环化合物的合成。
2)N-杂多并苯合成及其光电性能。如N-杂五并苯的合成及其半导体性能测试。
3)将农药分子中药效基团引入到课题组所合成的新型杂环骨架中,测试它们的生物活性。
招生学科:有机化学和农药学
Education:
BS Yangzhou University(1988-1992)
MS Nankai University (1994-1997)
PhD Nankai University (1997-2000)
Work Experience:
Teacher: The Third High School of Gaoyou City, Jiangsu Province (1992-1994)
Lecturer: Nankai University (2000-2002)
Postdoctoral Associate: University of Virginia (2006-2007)
Associate Professor: Nankai University (2002-).
主持并完成的项目:
1)国家自然科学基金:生物合理设计与类同合成相结合设计新型农药(No. 20302004)。
2)科技部(国家重大科技攻关项目):创制除草剂H-0306的研究(No. 2004BA308A23-13) 。
3)国家科技支撑计划课题:治理恶性杂草的生态农药创制开发(No. 2011BAE06B03).
4)天津市自然科学基金:氰基丙烯酸酯类除草剂的研究与开发(No. 043604111) 。
5)天津市自然科学基金:新型杂环并嘧啶酮(或三嗪酮)的合成及其抗肝癌活性(No. 11JCYBJC14200)。
参加了多项国家自然科学基金面上项目和国家重大科技攻关项目。主持多项横向课题。
发表论文80多篇,申请专利6项,授权专利4项。
SELECTED PUBLICATIONS
1. Xiaobing Yang, Fangzhong Hu*, Yang Wang, Chiming Yang*, Xiaomao Zou,, Jiahui Liu, Qichun Zhang*. Base-catalyzed cascade synthesis of 2,3-dihydrofuro[2,3-b]pyridines and 2,3-dihydro-1H-pyrrolo[2,3-b]pyridines from N-propargylic β-enaminones. Chem. Commun., 2017, 53, 7497-7500.
2. Xiaobing Yang, Yang Wang, Fangzhong Hu*, Xiaoli Kan, Chiming Yang, Jiahui Liu, Pei Liu ,Qichun Zhang*. Base-promoted intramolecular cyclization of Nalkyl, N-propargylic b-enaminones for the synthesis of polysubstituted pyrroles. RSC Adv. 2016, 6, 68454-68459.
3. Xiaoli Kan, Xiaobing Yang, Fangzhong Hu*, Yang Wang, Ying Liu, Xiaomao Zou, Hengyu Li, Hao Li, Qichun Zhang*. Et3N mediated synthesis of polysubstituted thiophenes from α-oxo ketene dithioacetals. Tetrahedron Lett.2015, 56(45), 6198-6201.
4. Shengqi Guo, Xue Chen, Fangzhong Hu*, Qichun Zhang*, Lu Liu*. Ultralong In2S3 Nanotubes on Graphene Substrate with Enhanced Electrocatalytic Activity. ACS Appl. Mater. Interfaces, 2015, 7 (36), 20164-20169.
5. Xiao Zhang, Yuxiao Yang, Shengqi Guo, Fangzhong Hu*, Lu Liu*. Mesoporous Ni0.85Se Nanospheres Grown in Situ on Graphene with High Performance in Dye-Sensitized Solar Cells. ACS Appl. Mater. Interfaces, 2015, 7 (16), 8457-8464.
6. Fangzhong Hu*, Xinxin Cheng, Zixia Niu, Xiaobing Yang, Dan Li, Lei Wan, Junxiao Li, Bin Liu, Xiaomao Zou, Huazheng Yang, Bin Li*. Synthesis and Herbicidal Activities of 3-(4-chloro-2-fluoro-5-substituted phenyl)benzo[d][1,2,3]triazin-4(3H)-one derivatives. J. Heterocyclic Chem., 2015, 52, 793-801
7. Xiaobing Yang, Fangzhong Hu*, Hongjing Di, Xinxin Cheng, Dan Li, Xiaoli Kan, Xiaomao Zou, Qichun Zhang*. A convenient base-mediated synthesis of 3-aryol-4-methyl (or benzyl)-2-methylthio furans from alpha-oxo ketene dithioacetals and propargyl alcohols via domino coupling/annulations. Org. Biomol. Chem., 2014, 12(44), 8947-8951.
8. Shengqi Guo, Tianzeng Jing, Xiao Zhang, Xiaobing Yang, Zhihao Yuan*, Fangzhong Hu*. Mesoporous Bi2S3 nanorods with graphene-assistance as low-cost counter-electrode materials in dye-sensitized solar cells. Nanoscale,2014, 6(23), 14433-14440.
9. Caixia Lin, Jiafang Zhu, Qingshan Li, Lihua Ao, Yanjuan Jin,Fengbo Xu*, Fangzhong Hu* ,Yaofeng Yuan*. 2,5-Bis(2-(diphenylphosphino)phenyl)-1,3,4-oxadiazole ligands and their Cu(I) complexes for Sonogashira coupling reaction. Appl. Organometal. Chem.2014, 28, 298–303.
10.Gang Li, Junkuo Gao, Fangzhong Hu*, Qichun Zhang*. Synthesis, Characterization, and Physical Properties of Two Novel Nonaheteroacene Derivatives. Tetrahedron Lett.2014, 55(1), 282-285.
11. Min Zhang, Fangzhong Hu*, Ting Zhao, Liuqing Yang, Huazheng Yang. Synthesis and Herbicidal Evaluation of 3-N-Substituted Amino-6-benzyloxypyridazine Derivatives. J. Heterocyclic Chem., 2014, 51, 1404-1409.
12. Gang Li, Guankui Long, Wangqiao Chen, Fangzhong Hu, Yongsheng Chen, Qichun Zhang*. A Concise Method for Synthesizing 1, 4, 8, 11-Tetraaza-6, 13-dioxapentacene Derivatives. Asian J. Organic Chemistry, 2013, 2(10), 852-856.
13. Gang Li, Ke Zheng, Chengyuan Wang, Kheng Swee Leck, Fangzhong Hu*, Xiaowei Sun*, Qichun Zhang*. Synthesis and Nonvolatile Memory Behaviors of Dioxatetraazapentacene Derivatives. ACS Appl. Mater. Interfaces, 2013, 5 (14), 6458-6462.
14. Yuechao Wu, Zongyou Yin, Jinchong Xiao, Yi Liu, Fengxia Wei, Kejie Tan, Christian Kloc. Ling Huang, Qingyu Yan, Fangzhong Hu*, Qichun Zhang*. Crystal Structure and Phototransistor Behavior of N-Substituted Heptacence. ACS Appl. Mater. Interfaces, 2012, 4 (4), 1883-1886.
授权专利:
(1)胡方中,杨华铮等,Z-2-氰基-3-(N-(S)-?-甲基对氟苄胺基)-2-戊烯酸乙氧乙酯合成及除草活性. CN 100486958C, 2009.
(2)胡方中,李春晖等. 3-取代苯氧苄胺基-2-氰基丙烯酸乙氧乙酯类化合物的合成及除草活性. CN 101967115, 2013.
(3)胡方中,古国贤等. 2-氰基-3-烷氧基-3‘-芳甲胺基丙烯酸酯的合成及除草活性. CN 101659636, 2014.
(4)胡方中,申志祥等. 一种合成?-芳基丙烯酰胺类化合物的方法. CN201110357595.2, 2015.
参编专著两部(《农药分子设计》、《现代农药化学》)。
已培养硕士生17名,本科生7名。