Address：94 Weijin Road

Telephone：022-23501520

Email：zhengjiehe@nankai.edu.cn

Website：http://skleoc.nankai.edu.cn/professors/hezhengjie/hezj.htm

Research Interest：

Research Interest Areas:

1. Organophosphorus Chemistry;

2. Organic Synthetic Chemistry;

3. Medicinal Chemistry

1985—1989     Central China Normal University, Chemistry

                         Dept., undergraduate

1989—1994     Institute of Elemento-Organic Chemistry,

                         Nankai University, graduate

1994—1998     Nankai University, associate professor

1998—2004     University of Pretoria (SA, 1998-1999),

                        Marquette University (USA, 1999-2003),

                        Purdue University (USA, 2003-2004),

                        postdoctoral associate

2004—present   Chemistry College, Nankai University,

                           professor

More than 120 peer-reviewed research papers have been published.Selected publications are listed as follows.

1. Enantioselective [4+1] annulation of α,β-unsaturated imines with allylic carbonates catalyzed by a hybrid p-chiral phosphine oxide-phosphine, H. Li, J. Luo, B. Li, X. Yi, Z. He, Org. Lett. 2017, 19, 5637-5640.

2. P(NMe2)3-mediated reductive (1+4) annulation reaction of isatins with nitroalkenes: an access to spirooxindolyl isoxazoline N-oxides and their corresponding isoxazolines, Y. Liu, H. Li, X. Zhou, Z. He, J. Org. Chem. 2017, 82, 10997-11007.

3. Phosphine-catalyzed (4 + 1) annulation of o-hydroxyphenyl and o-aminophenyl ketones with allylic carbonates: syntheses and transformations of 3-hydroxy-2,3-disubstituted dihydrobenzofurans and indolines, Z. Qin, W. Liu, D. Wang, Z. He, J. Org. Chem. 2016, 81, 4690-4700.

4. Divergent reactivity of nitrocyclopropanes with Huisgen zwitterions and facile syntheses of 3-alkoxy pyrazolines and pyrazoles, C. Yang, W. Liu, Z. He, Z. He, Org. Lett. 2016, 18, 4936-4939.

5. Annulation reaction of 3-acylmethylidene oxindoles with Huisgen zwitterions and its applications in the syntheses of pyrrolo[4,3,2-de]quinolinones and marine alkaloids Ammosamides, C. Yang, X. Chen, T. Tang, Z. He, Org. Lett. 2016, 18, 1486-1489.

6. P(NMe2)3-mediated reductive [1 + 4] annulation of isatins with enones: facile synthesis of spirooxindole-dihydrofurans, R. Zhou, K. Zhang, Y. Chen, Q. Meng, Y. Liu, R. Li, Z. He, Chem. Commun. 2015, 51, 14663-14666.

7. Diastereoselective synthesis of functionalized spirocyclopropyl oxindoles via P(NMe2)3-mediated reductive cyclopropanation, R. Zhou, C. Yang, Y. Liu, R. Li, Z. He, J. Org. Chem., 2014, 79, 10709-10715.

8. Phosphine-catalyzed [4+1] annulation of 1,3-(aza)dienes with maleimides: highly efficient construction of azaspiro[4.4]nonenes, M. Yang, T. Wang, S. Cao, Z. He, Chem. Commun. 2014, 50, 13506-13509.