Wang Liang
Special Talent：
Address：Integrated Laboratory building C524, Nankai University at Jinnan, Haihe Educational Park, Tianjin
Telephone：022-85358387
Email：lwang@nankai.edu.cn
Research Group Website：
Research Interest：
1. Medicinal Chemistry of Anti-Cancer Natural Products
2. Target Identification of Complex Natural Products
3. Total Synthesis of Natural Products
2007.9-2011.7 Shandong University, B.S., P. R. China;
2011.9-2016.7: Nankai University, Ph. D., P. R. China;
2016.7-2018.12: Lecturer at College of Pharmacy, Nankai University, Tianjin, P. R. China;
2018.12- 2020.10: Associate Prof. at College of Pharmacy, Nankai University, Tianjin, P. R. China;
2020.10-Present: Associate Prof. at College of Chemistry, Nankai University, Tianjin, P. R. China;
1. Junhong Xiang, Yahui Ding*, Jiaxin Li, Xiuhe Zhao, Yuanjun Sun, Da Wang, Liang Wang*, and Yue Chen*, Ovatodiolides: Scalable Protection-free Syntheses, Configuration Determination and Biological Evaluation against Hepatic Cancer Stem Cells. Angew. Chem. Int. Ed., 2019, 131, 10697.
2. Yuanjun Sun1, Yahui Ding1, Dongmei Li, Ruifei Zhou, Xiuwen Su, Juan Yang, Xiaoqian Guo, Chuanke Chong, Jinghan Wang, Weicheng Zhang, Cuigai Bai, Liang Wang*, Yue Chen*, Cyclic Depsipeptide BE-43547A2: Synthesis and Activity against Pancreatic Cancer Stem Cells. Angew. Chem. Int. Ed., 2017, 56, 14627. (Hot paper, Press Release Paper)
3. Liang Wang, Hengtao Wang, Yi Hang Li, and Pingping Tang*, Total Synthesis of Schilancitrilactones B and C. Angew. Chem. Int. Ed., 2015, 54, 5732.
4. Jinghan Wang, et al., Liang Wang*, Guang Yang*, Yue Chen*, Total Syntheses and Biological Activities of Vinylamycin Analogs. J. Med. Chem., 2017, 60, 1189.
5. Junhong Xiang, et al., Liang Wang*, Yue Chen*, Rapid Construction of the Scaffold of Quorumolide A Enabled by a Tandem ROM/RCM ******** and a Tandem Oxidative Cyclization ********. Org. Lett., 2019, 21, 6485.6. Baijun Ye, et al., Liang Wang*, Yue Chen*, Total Synthesis of the Highly N-Methylated Peptide Jahanyne. J. Org. Chem., 2018, 83, 6741.
7. Junhong Xiang, Xuemei Zhang, Dehong Wang, Jiaxin Li, Qiuying Li, Qin Wang, Yahui Ding*, Tianyang Chen, Yuanjun Sun, Shiqi Bao, Jing Chen, Dongmei Li, Liang Wang*, Yue Chen*, Chemical modification of ovatodiolide revealed a promising amino-prodrug with improved pharmacokinetic profile. Chem. Comm., 2020, 56, 11018.
Address: 94 Weijin Road, Tianjin 300071, CHINA
TEL: +86-22-2350 8470 E-mail: nkchem@nankai.edu.cn