蒋玲艳

蒋玲艳，女，副研究员，硕士生导师。 2006年毕业于西北大学生命科学与技术基地班，获学士学位； 2014年毕业于南开大学生物化学与分子生物学专业，获博士学位。2015年在南开大学生态学博士后流动站进行博士后研究工作，2017年留校任教，现为泰达生物技术研究院副研究员。

长期从事病原菌的致病机理及病原菌与宿主细胞的互作机制研究，以第一/通讯作者在Nature Communications, PLoS Pathogens, Gut Microbes, Communications Biology等高水平期刊发表30多篇论文。作为负责人主持省部级以上项目4项，包括2项国家自然科学基金，1项天津市基金，1项博士后科学基金。作为课题骨干参与2项国家科技重点研发计划项目、1项国家自然科学基金重点项目。2018年入选天津市“131”创新型人才培养工程第三层次人选。

联系方式：Email：jianglingyan@nankai.edu.cn ； 电话：022-65333286  

近期代表性论文：

Lingyan Jiang, Peisheng Wang, Xiaorui Song, Huan Zhang, Shuangshuang Ma, Jingting Wang, Wanwu Li, Runxia Lv, Xiaoqian Liu, Shuai Ma, Jiaqi Yan, Haiyan Zhou, Di Huang, Zhihui Cheng, Chen Yang, Lu Feng^*, Lei Wang^*. Salmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence. Nature Communications, 2021, 12(1):879. (IF: 17.694 一区Top)

Lingyan Jiang, Wanwu Li, Xi Hou, Shuai Ma, Xinyue Wang, Xiaolin Yan, Bin Yang, Di Huang, Bin Liu, Lu Feng^*. Nitric oxide is a host cue for Salmonella Typhimurium systemic infection in mice. Communications Biology. 2023, 6(1):501. (IF: 6.548 一区)

Lingyan Jiang, Wen Yang, Xinlei Jiang, Ting Yao, Lu Wang, Bin Yang^*. Virulence-related O islands in enterohemorrhagic Escherichia coli O157:H7. Gut Microbes. 2021,13(1):1992237. (IF: 9.434 一区Top)

Zhiqiu Yin, Si Zhang, Yi Wei, Meng Wang, Shuangshuang Ma, Shuang Yang, Jingting Wang, Chao Yuan^*, Lingyan Jiang^*, Yuhui Du^*. Horizontal gene transfer clarifies taxonomic confusion and promotes the genetic diversity and pathogenicity of Plesiomonas shigelloides. mSystems. 2020, 5:e00448–20. (IF: 7.324 二区)

Shuangshuang Ma, Lingyan Jiang (Co-first author), Jingting Wang, Xiaoqian Liu, Wanwu Li, Shuai Ma, Lu Feng^*. Downregulation of a novel flagellar synthesis regulator AsiR promotes intracellular replication and systemic pathogenicity of Salmonella typhimurium. Virulence. 2021, 12(1):298–311. (IF: 5.428 二区)

Wanwu Li, Lingyan Jiang (Co-first author), Xiaoqian Liu, Rui Guo, Shuai Ma, Jingting Wang, Shuangshuang Ma, Shujie Li, and Huiying Li^*. YhjC is a novel transcriptional regulator required for Shigella flexneri virulence. Virulence. 2021, 12(1): 1661–1671. (IF: 5.428 二区)

Jingting Wang, Shuai Ma, Wanwu Li, Xinyue Wang, Di Huang, Lingyan Jiang ^*, Lu Feng^*. Salmonella enterica serovar Typhi induces host metabolic reprogramming to increase glucose availability for intracellular replication. International Journal of Molecular Sciences. 2021, 22: 10033.  (IF:6.208 二区)

Lingyan Jiang, Peisheng Wang, Xiaomin Li, Runxia Lv, Lin Wang, Bin Yang, Di Huang, Lu Feng^*, Bin Liu^*. PagR mediates the precise regulation of Salmonella pathogenicity island 2 gene expression in response to magnesium and phosphate signals in Salmonella Typhimurium. Cellular Microbiology. 2019, 22(2):e13125. (IF: 4.115 二区)

Chao Yuan, Zhiqiu Yin, Junyue Wang, Chengqian Qian, Yi Wei, Si Zhang, Lingyan Jiang^*, Bin Liu^*. Comparative genomic analysis of Citrobacter and key genes essential for the pathogenicity of Citrobacter koseri. Frontiers in Microbiology. 2019, 10:2774. (IF: 6.064  二区)

Lingyan Jiang, Lu Feng, Bin Yang, Wenwen Zhang, Peisheng Wang, Xiaohan Jiang, Lei Wang^*. Signal transduction pathway mediated by the novel regulator LoiA for low oxygen tension induced Salmonella Typhimurium invasion. PLoS Pathogens. 2017, 13(6):e1006429. (IF: 7.464 一区Top)